Immune checkpoint inhibition; a novel approach to fighting cancer

The Nobel prize for medicine went to 2 researches who developed ways for our own innate immune system to fight off certain types of cancer.  In a shift away from the classic “chemotherapy” approach, this new approach called “immune checkpoint inhibition”, blocks the ability of a cancer cell to turn off the immune system.  When checkpoint inhibition is turned off by a manufactured blocking antibody (the therapeutic drug), the T cell can then go after the cancer cell and suppress/remove it.  See the attached article from Nature.

https://www.nature.com/articles/d41586-018-06751-0

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